Personalising the ventilator settings to the patient by a simple measure of pressure in their foodpipe(esophagus) during a surgery
Phase 2
- Conditions
- Health Condition 1: K00-K95- Diseases of the digestive systemHealth Condition 2: N00-N99- Diseases of the genitourinary system
- Registration Number
- CTRI/2019/08/020556
- Lead Sponsor
- A
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
American society of Anaesthesiologists physical status I and II
- Scheduled for laparoscopic pelvic surgery
Exclusion Criteria
- Refusal to participate
- Coexisting pulmonary, cardiovascular or oesophageal pathology
- Previous oesophageal or pulmonary operation
- Patient BMI less than 18 or BMI more than 30
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To compare the effect of TPP guided PEEP application and conventional PEEP application (at 5cm H2O) on postoperative oxygenation parameters (PaO2/FiO2 ratio, A-aDO2, and SpO2)Timepoint: Baseline, 15 min post pneumo peritoneum, 15 min post Trendelenburg position, 30 min post shifting to Post-op area
- Secondary Outcome Measures
Name Time Method To compare the effect of TPP guided PEEP application on intra-operative hemodynamic parameters of the patient [Mean Blood Pressure (MAP), Heart Rate (HR) and Pulse Pressure (PP)]Timepoint: Baseline, 15 min post pneumo peritoneum, 15 min post Trendelenburg position, 30 min post shifting to Post-op area;To compare the effect of TPP guided PEEP application on intra-operative respiratory mechanical parameters [Lung compliance (CL), Respiratory system Compliance (CRS), Chest wall Compliance (CCW), Lung Elastance (EL), Respiratory system Elastance (ERS), Chest wall Elastance (ECW), Plateau Pressure (PPLAT) and Peak Pressure (PPEAK)]Timepoint: Baseline, 15 min post pneumo peritoneum, 15 min post Trendelenburg position, 30 min post shifting to Post-op area