The role and therapeutic implications of Shenfu cinjection in the treatment of sepsis

Phase 4

Completed

• Conditions: sepsis

• Registration Number: ITMCTR2200006018
• Lead Sponsor: Renji Hospital, School of Medicine, Shanghai Jiaotong University

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 20 February 2023

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: Not specified

Inclusion Criteria

(1)18 years<age<75 years;(2)diagnosis with septic shock (3) SFI were not used within 24 hours after hostapilization (4) recuit in EICU within 24 hours

Exclusion Criteria

(1) hypersensitivity to SFI; (2) the administration of other type of chinese medicine (3)palliative and end-life stage patients (4)pregnant and lactating women (5) patients with myocadrdial infarction or acute coronary syndrome (6)long-term use of immunosuppressive drugs or hormonal drugs (7) Patients with advanced malignancies (8) participants or thier agents are unable or unwilling to sign the informed consent document.

Study & Design

• Study Type: Interventional study
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
28-day mortality;

Secondary Outcome Measures

Name	Time	Method
Syndecan-1;sublingual microcirculation;Angiopoietin-1;IL-6;PCT;WBC;Endothelin-1;Angiopoietin-2;CRP;