Effect of Prednisolone and Promethazine in Hyperemesis Gravidarum: A Double Blind Clinical Trial Study
Phase 3
- Conditions
- Hyperemesis gravidarum.Excessive vomiting in pregnancy
- Registration Number
- IRCT201104231760N12
- Lead Sponsor
- Vice Chancellor for Research and Technology
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- Female
- Target Recruitment
- 70
Inclusion Criteria
Women 18 to 35 years, First or second pregnancy, Less than 16 weeks gestational age according to last menstrual period and ultrasound, Vomiting more than three times a day with no response to outpatient treatment, Weight loss over 3 kg and a positive urine ketone. Exclusion criteria: Concurrent Medical diseases, Anti-emetic drugs with in three days, Hydatid form mole, Twin pregnancy and iron supplementation.
Exclusion Criteria
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Severity of nausea and vomiting. Timepoint: The first day, second, third, fourth, 14th (end of treatment) and 28th (two weeks after treatment). Method of measurement: Visual Analoge Scale and the number of vomiting per day.
- Secondary Outcome Measures
Name Time Method