Effects of Repetitive Transcranial Magnetic Stimulation combined with Action Observation Execution on Upper Extremity Motor Function in stroke: A Double-blinded Randomized Controlled Trial

Mahidol University0 个研究点目标入组 22 人开始时间: 2024年4月16日最近更新: 2024年8月19日

适应症

试验速览

暂无简介。

•1. First subcortical stroke within 1-3 months as reported by the CT/ MRI
•2. Age between 40-80 years
•3. Right-handed based on the Edinburgh Handedness Inventory
•4. Being able to understand and follow simple commands based on performance on the mini-mental state examination(MMSE) (cutoff>23)
•5. Fugl-Meyer Assessment (FMA) upper extremity level at moderate (29-42 scores)
•6. Normal visual field and hearing
•7. Independent sitting for at least 1 hour

•1. No contraindications of using rTMS (seizure, an intracranial metallic implant, MRI-incompatible pacemakers) 2. Other neurological problems (Parkinson's disease) 3. Severe sensory impairment (score = 0 by the FMA-UE of sensation and proprioception) 4. Severe joint pain on at least 3 of 5 UE joints (FMA-UE pain score=0) 5. Severe limited joint movement (FMA-UE passive joint motion of shoulder and elbow score=0) 6. Aphasia 7. Visual neglect ( screening by NIHSS-neglect score more than 1) 8. Ideomotor apraxia ( imitation meaningless of gesture; error score > 3)

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