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Aesthetic Effect of Steri-Strip Orientation on Healing and Scar Appearance in Breast Surgery

Not Applicable
Completed
Conditions
Breast Diseases
Surgical Wound
Scar
Breast Neoplasms
Interventions
Device: Steri-strip
Registration Number
NCT04554316
Lead Sponsor
Albert Einstein Healthcare Network
Brief Summary

All patients undergoing breast biopsy, lumpectomy, needle-localization-guided breast biopsy, and mastectomy at Einstein Medical Center Philadelphia, Einstein Medical Center Montgomery, Center One, or Einstein Elkins Park will be offered participation into the study. Patients who have documented allergies to adhesive or tape, patients taking chronic steroids, and patients with documented connective tissue, skin, or healing disorders will be excluded from the study. Risks and benefits of the study as well as risks and benefits of the procedure will be discussed with the patient by one of the investigators. If the patient elects to participate in the study, they will be assigned to incisional dressing at the time of operation with either in-line or perpendicular placement of Steri-Strips based on the patient's computer-generated randomization assignment. The patient's chart will be reviewed to determine the patient's age and comorbid conditions including obesity (pre-operative BMI), diabetes mellitus, use of anti-platelet or anticoagulant medication, or smoking. This information will be utilized to ensure that our study groups are similar in baseline demographics and pre-existing conditions. Additionally, the primary medical reason for needing breast surgery will be reviewed as well as treatment with pre-operative or post-operative chemotherapy or radiation therapy to the breast. Steri-Strips will not be removed and will be allowed to fall off naturally. At regularly scheduled 30-day and 90-day follow-up appointments, pictures will be taken of the incisional area. These photographs will be reviewed by a blinded, independent surgeon who will grade each incision according to the modified Hollander Cosmesis Scale. Statistical analysis with t-testing of the means and chi-squared testing of dichotomous variables will be performed to determine significance of the findings.

Detailed Description

Not available

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
94
Inclusion Criteria
  • All adult patients undergoing breast biopsy, lumpectomy, needle-localization-guided breast biopsy, and mastectomy at Einstein Medical Center Philadelphia, Einstein Medical Center Montgomery, Center One, or Einstein Medical Center Elkins Park will be offered participation into the study.
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Exclusion Criteria
  • Patients who have documented allergies to adhesive or tape, patients taking chronic steroids, and patients with documented connective tissue, skin, or healing disorders
  • members of vulnerable populations such as adults who are unable to consent, individuals who are not yet adults, pregnant women, or prisoners
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Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Arm && Interventions
GroupInterventionDescription
Parallel placementSteri-stripSteri-strips will be placed in-line (parallel) with the surgical incision.
Perpendicular placementSteri-stripSteri-strips will be placed perpendicular to the surgical incision.
Primary Outcome Measures
NameTimeMethod
Cosmesis score 30 days30 days

Hollander cosmesis scale (0-6, 6 being best cosmetic grade) grade of scar appearance at 30 days

Cosmesis score 90 days90 days

Hollander cosmesis scale (0-6, 6 being best cosmetic grade) grade of scar appearance at 90 days

Secondary Outcome Measures
NameTimeMethod
Wound dehiscence90 days

Presence or absence of wound dehiscence

Surgical site infection90 days

Presence or absence of surgical site infection

Trial Locations

Locations (2)

Albert Einstein Medical Center Montgomery

🇺🇸

East Norriton, Pennsylvania, United States

Albert Einstein Medical Center

🇺🇸

Philadelphia, Pennsylvania, United States

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