Effectiveness of Dental Brushing for Preventing Ventilator-Associated Pneumonia

Phase 2

• Conditions: Ventilator-Associated Pneumonia; Nosocomial Pneumonia; Pneumonia
• Interventions: Procedure: Toothbrushing

• Registration Number: NCT00842478
• Lead Sponsor: Hospital Universitari Joan XXIII de Tarragona.

Brief Summary

Poor oral hygiene is associated with respiratory pathogen colonization and secondary lung infection.The possible association between oral care and incidence of VAP, and the role of dental plaque, mouth and tracheal colonization have not been firmly established. The investigators' hypothesis was that improving oral care with electrical toothbrushing might be effective in reducing the incidence of VAP.

Detailed Description

Not available

Study Timeline

• Study Start: 2005-05
• Status Verified: 2009-02
• Study First Submitted: 2009-02-11
• Study First Submitted QC: 2009-02-11
• Last Update Submitted: 2009-02-11
• Study First Posted: 2009-02-12
• Last Update Posted: 2009-02-12

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 400

Inclusion Criteria

• Adult intubated patients
• Without evidence of pulmonary infection (randomized within 12h of intubation if they were expected to remain ventilated for longer than 48 hours)

Exclusion Criteria

• Absence of dental pieces
• Current diagnosis of pneumonia or massive bronchoaspiration
• Tracheostomy (or expected within 48 hours)
• Chlorhexidine allergy

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Raspall	Toothbrushing	-

Primary Outcome Measures

Name	Time	Method
Ventilator-Associated Pneumonia (VAP)	28 days

Trial Locations

Locations (1)

ICU, Hospital Universitari Joan XXIII; 🇪🇸 Tarragona, Spain