ESTIMATION OF SALIVARY BIOMARKERS microRNA 146a,17, 21 IN PERIODONTITIS AMONG TYPE II DIABETES MELLITUS AND NON-DIABETIC PATIENTS
Not Applicable
- Conditions
- Health Condition 1: E00-E89- Endocrine, nutritional and metabolic diseases
- Registration Number
- CTRI/2023/03/050457
- Lead Sponsor
- il
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
1. Patients who are diagnosed with Periodontitis
2. Patients who are diagnosed with Type II Diabetes based on ADA criteria with the age group of
30-50 years.
3. Non-diabetic subjects.
Exclusion Criteria
1. Patients with a history of acute or chronic inflammatory diseases
2. Patients who are smokers.
3. Patients who are under chronic medications which influence salivary flow
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Identifying the potential risk of periodontitis among Type 2 diabetes <br/ ><br>mellitus and non-diabetic based on salivary biomarker MiRNA 146a ,17 and 21 <br/ ><br>Timepoint: 1 year
- Secondary Outcome Measures
Name Time Method nilTimepoint: nil
Related Research Topics
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Role salivary miR-146a miR-17 miR-21 inflammation pathophysiology periodontitis type 2 diabetes
Diagnostic prognostic value salivary miR-146a miR-17 miR-21 periodontitis T2DM patients
Salivary microRNAs versus GCF cytokines biomarkers periodontitis severity type 2 diabetes
Correlation salivary miR-146a miR-17 miR-21 levels glycemic control periodontal status T2DM
MicroRNA regulation inflammatory response NF-kB pathway periodontitis diabetes mellitus link