Endometrial Sampling (Pipelle)in IVF Patients

Not Applicable

• Conditions: Infertility

• Registration Number: NCT00411021
• Lead Sponsor: Sheba Medical Center

Brief Summary

A prospective cross-over randomized study aimed to test the hypothesis that local injury of the endometrium increases the implantation rate in the successive cycle. Seventy IVF patients will be randomly selected to undergo either endometrial biopsies or minimal cervical scratch on days 8-10 and 21-23 of their cycle, preceding the IVF treatment. If not pregnant, the women will continue for another IVF cycle, preceded by endometrial or cervical scratch complimentary to their procedure in the first cycle. The main major outcomes will include pregnancy rate, implantation rate, endometrial thickness, abortion rate, live births and embryo quality.

Detailed Description

Not available

Study Timeline

• Status Verified: 2006-12
• Study First Submitted: 2006-12-12
• Study First Submitted QC: 2006-12-12
• Last Update Submitted: 2006-12-12
• Study First Posted: 2006-12-13
• Last Update Posted: 2006-12-13

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: Female
• Target Recruitment: 70

Inclusion Criteria

• Women undergoing IVF treatment
• Repeated Implantation failure

Exclusion Criteria

• PID or suspected PID
• Undiagnosed Irregular Bleeding

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: CROSSOVER

Trial Locations

Locations (1)

IVF Unit, Sheba Medical Center; 🇮🇱 Ramat-Gan, Israel