The comparison of success rate of treatment of Graves disease with fixed dose radioiodine therapy between protocol 1 and protocol 2 in EEC regio

Recruiting

• Conditions: The success rate of fixed dose radioiodine therapy is about 70% and how increasing it; Graves disease; success rate of fixed dose of radioiodine therapy

• Registration Number: TCTR20220527002
• Lead Sponsor: Queen Savang Memorial Vadhana Hospital

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2022-05-27
• Study Completion: 2022-12-31
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 650

Inclusion Criteria

1. the patient was diagnosed as Graves disease and getted indication for radioiodine therapy including thyroid strom, thyrotoxicosis periodic paralysis, side effects from anti-thyroid drugs and relapse ,recurrent or incomplete remission of Graves disease.
2. No contraindication for radioiodine therapy including pregnancy, lactation, moderate-to-severe Graves opthalmopathy.
3. patient hadn't been treated with radioiodine therapy.

Exclusion Criteria

1. loss-to-follow up is less than 5 months.

Study & Design

• Study Type: Observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Success rate of The treatment of fixed dose radioiodine therapy 5-6 months Euthyroidism or Hypothroidism from Thyroid function test

Secondary Outcome Measures

Name	Time	Method
Success rate of The treatment of fixed dose radioiodine therapy 12 months Euthyroidism or Hypothroidism from Thyroid function test,Comparison between incidence of hypothyroidism after fixed dose radioiodine therapy protocal 1 and protocal 2 12 months Hypothroidism from Thyroid function test,The Failure factor of Protocol 2 fixed dose radioiodine therapy 12 months Baseline characteristic in Protocol 2