The comparison of treatment success rate of injection of hyaluronic acid versus PRP for patients with TMJ osteoarthritis.
Phase 2
Recruiting
- Conditions
- Temporomandibular joint osteoarthritis.Temporomandibular joint disorders
- Registration Number
- IRCT20150613022697N6
- Lead Sponsor
- Mashhad University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 30
Inclusion Criteria
All of the patients with TMJ osteoarthritis (in one or both Joints) with age range 15-60 years old who received conservative treatment.
Patients with ASA 1 or 2 status
Patients with normal cardiovascular or coagulation system
Exclusion Criteria
Patients with previous TMJ surgery
Patients with the history of neurological, immunologic head & neck and TMJ malignancy
Patients with the history of problem in connective tissue such as rheumatoid arthritis
Patients with the history of NSAIDS usage.
Patients with the allergy to HA and PRP
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Maximum Mouth Opening (MMO) rate. Timepoint: One day before, 1, 3, 6 and 12 months after arthrocentesis. Method of measurement: Ruler in millimeters.;Jaw protrusive movement rate. Timepoint: One day before, 1, 3, 6 and 12 months after arthrocentesis. Method of measurement: Ruler in millimeters.;Jaw lateral Movement rate. Timepoint: One day before, 1, 3, 6 and 12 months after arthrocentesis. Method of measurement: Ruler in millimeters.;Joint sounds presence. Timepoint: One day before, 1, 3, 6 and 12 months after arthrocentesis. Method of measurement: Yes / No.;Joint pain amount. Timepoint: One day before, 1, 3, 6 and 12 months after arthrocentesis. Method of measurement: VAS scale.
- Secondary Outcome Measures
Name Time Method