Effect of pomegranate flower syrup in preventing mucositis
Phase 2
- Conditions
- Mucositis caused by radiotherapy.
- Registration Number
- IRCT20221028056330N1
- Lead Sponsor
- Tehran University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- All
- Target Recruitment
- 120
Inclusion Criteria
The study of patients with head and neck cancers who are candidates for at least 50 Gy radiotherapy to the oral cavity with or without concurrent chemotherapy after surgery will be included in the study.
Exclusion Criteria
Patients who had a history of head and neck radiotherapy, opium addiction or methadone use, active mucosal disease in the radiotherapy area and people under 18 years of age are excluded from the study.
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Severity of mucositis according to who definition. Timepoint: Checking the severity of mucositis every week during radiotherapy. Method of measurement: Based on the definition of the severity of mucositis of the World Health Organization. Severity of mucositis based on who definition. Zero grade: The patient has no symptoms. Grade 1: Erythema and mouth burning (brief mucosal inflammation) Grade 2: Erythema and oral ulcers that still have the ability to eat solid foods. (Mild pain that requires painkillers.) Grade 3: Ulcers with extensive erythema who cannot swallow solid food. (Severe pain that requires strong pain relief) Grade 4: Mucositis has become very widespread and has made feeding completely impossible for the person, and at the same time that there is a need for hospitalization for him.
- Secondary Outcome Measures
Name Time Method