Effects of Quadratus Lumborum Block for Postoperative Pain Control in Patients Undergoing Elective Open Colorectal Surgery: A Randomized, double-blind controlled trial
- Conditions
- Postoperative pain control in colorectal surgery is one of the key components for ERAS(Enhanced recovery after surgery) protocol. Inadequate pain control may also lead topostoperative complications such as pulmonary complications, myocardial infarction, ileus aswell as transforming into persistent post surgical pain if not controlled.Quadratus Lumborum Block, Elective Open Colorectal Surgery, morphine consumption
- Registration Number
- TCTR20210824009
- Lead Sponsor
- Department of Anesthesiology
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 44
1. Patients aged between 40-80 years
2. Bodyweight more than 45 kg
3. ASA physical status between I-III
4. Written informed consent obtained from the patients I appreciate participating in
this study with the sign
1. Adults who are unable to give their own consent
2. Pre-existing lower extremities weakness
3. Patient who shows sign of infection at the site of QLB
4. BMI more than 40 kg/m2
5. Allergy or contraindication to any drug used in this study
6. Coagulopathy (assessed by history and physical examination and, if deemed
clinically necessary, by blood work up i.e. platelets less than and equal 100,000 cell/mm3,
INR more than and equal 1.4)
7. Chronic pain syndromes requiring chronic opioid use
8. Inability to use IV PCA device
9. History of kidney impairment (estimated GFR less than 60 ml/min)
10. History of liver dysfunction (history of cirrhosis, portal hypertension, or variceal
bleeding, AST, ALT more than and equal 50 IU/L)
11. Pregnancy
12. Refuse to participate or withdraw their consent at any stage of the study
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method cumulative morphine consumption during 24 h postoperatively at 24 hours after patient has arrived at recovery room quantitative measurement (mg)
- Secondary Outcome Measures
Name Time Method