Efficacy of niacin on phosphatic metabolism in patients with renal insufficiency
- Conditions
- Exam the efficacy of niaspan in phosphate metabolism of patients with renal insufficiency, different exam for dialysis and predialysis patients
- Registration Number
- EUCTR2005-002221-31-DE
- Lead Sponsor
- Clinic for Nephrology
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Recruiting
- Sex
- All
- Target Recruitment
- 30
Inclusion Criteria
age 18-90
chronic renal insufficiency
stable dose of calcium-containing phosphatbinding medication for the last four weeks
blood pressure<180/100mmHg
Are the trial subjects under 18? no
Number of subjects for this age range:
F.1.2 Adults (18-64 years) yes
F.1.2.1 Number of subjects for this age range
F.1.3 Elderly (>=65 years) yes
F.1.3.1 Number of subjects for this age range
Exclusion Criteria
intake from niacin during the last six months
dose-change for lipid-lowering therapy in the last six weeks
another clinical trial in the last 30 days
known drug use
pregnancy
known allergic reaction to niacin
liver function disturbances
lack of cooperation
Study & Design
- Study Type
- Interventional clinical trial of medicinal product
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Main Objective: phosphate and calcium metabolism;Secondary Objective: lipid metabolism;Primary end point(s): change in the serum phosphate level
- Secondary Outcome Measures
Name Time Method