PUBLIC TITLE ; Effect of niacin on hyperphosphatemia in chronic kidney disease (stages 3-5) patients
Phase 2
Recruiting
- Conditions
- Kidney Disease
- Registration Number
- PACTR201905507865682
- Lead Sponsor
- Edema Oritseweyinmi Great
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 120
Inclusion Criteria
Inclusion Criteria
CKD stages 3-5 patients who are aged 18 years -80 years.
Capable of giving informed consent
Serum phosphate levels 5-7 mg/dl
Unchanged treatment protocol (calcium carbonate and vitamin D) during last 2 weeks.
Exclusion Criteria
Unwillingness to participate in the study.
Pregnancy
Known liver disease,
Active peptic ulcer disease
Necessity of changing treatment protocol because of safety criteria (such as severe hyperphosphatemia or two consecutive serum phosphorus levels > 7 mg/dl)
Age greater than 80 years
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method mean change in serum phosphate levels from first to last week
- Secondary Outcome Measures
Name Time Method Secondary outcomeMean change in calcium, calcium-phosphate products and lipid profile parameters (HDL,LDL,TRYGLICERIDES