The effects of Nicotinic acid on serum phosphorus, PTH and lipid profile in dialysis patients .
Phase 2
- Conditions
- Condition 1: Hyperphosphatemi. Condition 2: Hyperlipidaemia. Condition 3: Hyperparathyroidism.Disorder of phosphorus metabolismMixed hyperlipidaemiaHyperparathyroidism and other disorders of parathyroid gland
- Registration Number
- IRCT201402212954N4
- Lead Sponsor
- Vice chancellor for research, Shahroud University medical and Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 120
Inclusion Criteria
Age > 15 &<70 years; sign satisfaction; serum phosphorous: 5-7 mg/dl; PTH level > 550 ug/ml; TG >350mg/ml; LDL>150mg/ml and HDL<25 mg/ml; unchanged treatment protocol; (calcium components and Vit D) during last two weeks; unchanged dialysis protocol. Exclusion criteria: pregnancy; known liver disease; active peptic ulcer; carbamazepine use; drug intolerance and not satisfaction of patients.
Exclusion Criteria
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Serum phosphate level. Timepoint: Twice a weeks for 3 months. Method of measurement: By standard kit in Imam Hossein hospital.;PTH level. Timepoint: Monthly for 3 months. Method of measurement: By standard kit in Imam Hossein hospital.;TG level. Timepoint: Start and end in 3 months. Method of measurement: By standard kit in Imam Hossein hospital.;LDL level. Timepoint: Start and end in 3 months. Method of measurement: By standard kit in Imam Hossein hospital.;HDL level. Timepoint: Start and end in 3 months. Method of measurement: By standard kit in Imam Hossein hospital.
- Secondary Outcome Measures
Name Time Method Serum Calsium level. Timepoint: Twice a weeks for 3 months. Method of measurement: By standard kit in Imam Hossein hospital.