Assessment of oral Nicotinamide effects on serum phosphorus in hemodialysis patients in Imam Khomeini and Golestan hospitals of Ahvaz in 2010
Phase 3
- Conditions
- Hemodialysis patients (ESRD).End-stage renal disease
- Registration Number
- IRCT138809172817N1
- Lead Sponsor
- Ahvaz Jondishapour University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 46
Inclusion Criteria
Age>18 years old, hemodialysis for more than 3 months, constant use of phosphate binder in recent two weeks, serum phosphorus>=5
Exclusion Criteria
liver disease or significant disturbance in liver function tests, active peptic ulcer, poor cooperation, severe diarrhea
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Serum phosphorus. Timepoint: week 0, 5 and 9 of the study. Method of measurement: serum phosphorus measurement by biochemistry autoanalyser.
- Secondary Outcome Measures
Name Time Method Serum iPTH. Timepoint: before and after the intervention. Method of measurement: Chemiluminescence iPTH measurement.;Serum lipids. Timepoint: before and after the intervention. Method of measurement: serum biochemistry by autoanalyser.