Physical Trainig and Cognitive Activity on the MCI Patient
Trial Snapshot
- Phase
- Not Applicable
- Status
- Terminated
- Enrollment
- 5
- Locations
- 1
- Primary Endpoint
- effectiveness of physical training
Study Overview
Brief Summary
Regular physical activity is now recognized as a key element of good physical and mental health and this all ages.
MAIN GOAL : Evaluate the effectiveness of physical training associated with a cognitive training in improving the cognitive function of patients diagnosed with Mild Cognitive Impairment (MCI).
DESIGN : Controlled randomized monocentric and prospective study with clinical benefit for the patient with three groups : one physical training and cognitive exercise group, one physical training without cognitive exercise group and one control group.
In agreement with the literature on the effects of physiological stress on cognitive performance, the investigators expect the best cognitive test scores in groups with exercise training compared with controls (35% versus 80% error), and better scores on the MMSE, IALD, depression Scale, Index of Pittsburg sleep quality and quality of Life Questionnaire. Furthermore the investigators hypothesize that this positive effect is greater in the physical training and cognitive exercise group compared with the physical training group only.
Study Design
- Study Type
- Interventional
- Allocation
- Randomized
- Intervention Model
- Parallel
- Primary Purpose
- Prevention
- Masking
- None
Eligibility Criteria
- Ages
- 40 Years to 75 Years (Adult, Older Adult)
- Sex
- All
- Accepts Healthy Volunteers
- No
Inclusion Criteria
- •Diagnosed patient MCI (Mild Cognitive Impairment)
- •Elderly from 40 to 75 years old
- •MMSE upper to 22
- •Affiliated or beneficiary of a national insurance scheme
- •Medical capacity to the physical proposed activity (filling of the conditions of the Medical certificate of not contraindication in the sport)
Exclusion Criteria
- •The placed persons under guardianship, under protection of justice,
- •The private persons of freedom (administrative or judicial)
- •Nobody already participating in a clinical trial
Arms & Interventions
control group
Intervention: control group (Other)
Physical and cognitive activity group
Intervention: Physical Training and cognitive activity (EPC group) (Other)
Physical activity group
Intervention: Physical training (EP group) (Other)
Outcomes
Primary Outcomes
effectiveness of physical training
Time Frame: up to 3 months
Assess the effectiveness of physical training associated with a cognitive training in improving the cognitive functions of patients diagnosed with Mild Cognitive Impairment (MCI). We expect the best cognitive test scores in groups with exercise training compared with controls (35% versus 80% error), and better scores on the MMSE, IALD, depression Scale, Index of Pittsburg sleep quality and quality of Life Questionnaire.
Secondary Outcomes
- Cognitive improvement(up to 3 months)