The Effect of Physical Activity on the Mental and Physical Health of Children With Cancer in Remission
Trial Snapshot
- Phase
- Not Applicable
- Status
- Completed
- Enrollment
- 22
- Primary Endpoint
- health-related quality of life
Study Overview
Brief Summary
Physical activity is a well-known and powerful tool in medicine,having preventive, palliative, and curative properties. This has not been sufficiently examined in children in remission from cancer. In this study, children in remission from cancer will be divided into exercise and control groups. The interventional group will perform two supervised, 60-minute weekly exercise sessions. Outcome measures of the exercise intervention will be quality of life, mood, cardiorespiratory fitness, body composition and bone mineral density.
Study Design
- Study Type
- Interventional
- Allocation
- Non Randomized
- Intervention Model
- Parallel
- Primary Purpose
- Treatment
- Masking
- None
Eligibility Criteria
- Ages
- 6 Years to 16 Years (Child)
- Sex
- All
- Accepts Healthy Volunteers
- No
Inclusion Criteria
- •children aged 6-16
- •remission from cancer
- •>6 months after completion of all therapy
Exclusion Criteria
- •informed consent not given in writing
- •refusal of tests: blood, fitness, questionnaires or DEXA
- •locomotive handicaps
- •extreme fatigue, nausea, dyspnea
- •concurrent acute illness
- •recent (less than 3 months) hospitalization
- •documented (echocardiographic or nuclear medicine) decrease in cardiac function
- •abnormal blood tests: Hb < 10 gr/dl, neutropenia < 500/mm3, thrombocytopenia < 50,000/mm3
- •additional chronic health conditions unrelated to cancer (e.g. celiac disease, cerebral palsy, Down's syndrome)
Arms & Interventions
exercise
two supervised, 60-minute weekly exercise sessions + instructions to perform additional physical activities throughout the day
Intervention: exercise (Behavioral)
control
no intervention
Outcomes
Primary Outcomes
health-related quality of life
Time Frame: 6months
mood
Time Frame: 6months
cardiorespiratory fitness
Time Frame: 6months
body fat percentage
Time Frame: 6months
bone mineral density
Time Frame: 6months
Secondary Outcomes
No secondary outcomes reported
Investigators
gal dubnov raz
Senior physician
Sheba Medical Center