NCT03658343已完成不适用
An Exploratory, Pilot Study Evaluating T2* Imaging for Adult Sarcoma
Bryan Allen1 个研究点 分布在 1 个国家目标入组 8 人开始时间: 2018年9月18日最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 8
- 试验地点
- 1
- 主要终点
- Change in ferric iron levels detected by T2* MRI
研究概览
简要总结
T2* imaging is a method to identify labile iron pools in tumor cells. These iron pools may be linked to better treatment outcomes for specific types of therapy. This is a small pilot study to see if radiation therapy changes the amount of iron in a sarcoma tumor.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •pathologically confirmed Sarcoma, by biopsy or excision
- •prescribed radiation therapy as per standard of care
- •treatment to begin within 5 weeks after surgery or biopsy
- •ECOG 0, 1, or 2
- •ability and willingness to provide informed consent
排除标准
- •< 18 years of age
结局指标
主要结局
Change in ferric iron levels detected by T2* MRI
时间窗: baseline and 8 weeks
Change from baseline in Fe3+ iron levels
次要结局
- Change in ferrous iron levels detected by T2* MRI(Baseline and 8 weeks)
研究者
Bryan Allen
Assistant Professor
University of Iowa
研究点 (1)
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