Ventricular Remodeling and Heart Failure After Myocardial Infarction: a Community Study

Active, not recruiting

• Conditions: Myocardial Infarction; Heart Failure

• Registration Number: NCT02047396
• Lead Sponsor: Mayo Clinic

Brief Summary

To comprehensively characterize Left Ventricular (LV) remodeling after Myocardial Infarction (MI) in the community, study the association between patterns of remodeling and biological pathways and examine the association between the predictors of remodeling and heart failure after Myocardial Infarction.

Detailed Description

Not available

Study Timeline

• Study Start: 2014-01
• Study First Submitted: 2014-01-23
• Study First Submitted QC: 2014-01-24
• Study First Posted: 2014-01-28
• Primary Completion: 2018-08-31
• Status Verified: 2025-02
• Last Update Submitted: 2025-02-17
• Last Update Posted: 2025-02-19
• Study Completion: 2030-01

Recruitment & Eligibility

• Status: ACTIVE_NOT_RECRUITING
• Sex: All
• Target Recruitment: 1599

Inclusion Criteria

1. Hospitalized patients with a clinical diagnosis of Myocardial Infarction.
2. Residents of Olmsted, Dodge, Goodhue, Wabasha, Winona, Fillmore and Mower Counties.
3. Able to provide informed consent.

Exclusion Criteria

1. Previous clinical diagnosis of Myocardial Infarction
2. Previous diagnosis of Heart Failure and/or Cardiomyopathy
3. Diagnosis of Apical Ballooning Syndrome
4. Planned Coronary Artery Bypass Graft (CABG) during index hospitalization
5. Unable to provide informed consent

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Heart Failure	5 years	Development of Heart Failure post Myocardial Infarction

Secondary Outcome Measures

Name	Time	Method
Death	5 years	All cause mortality post Myocardial Infarction

Trial Locations

Locations (1)

Mayo Clinic; 🇺🇸 Rochester, Minnesota, United States