An Exploratory Clinical Study for The Development of the Diagnostic Method for Lymphatic-vessel Lesions Using Photoacoustic Imaging

Not Applicable

• Conditions: lymphedema

• Registration Number: JPRN-UMIN000030500
• Lead Sponsor: Keio University

Brief Summary

Regarding the scientific validity, the lymphatic vessel images of healthy subjects and patients obtained by taking photoacoustic imaging were published in Radiology and Journal of Surgical Oncology. The finding of lymphatic pump were also published in Plastic and Reconstructive Surgery Global Open. In addition, the relationship between the lymphatic vessel images obtained by optical ultrasound imaging and the images obtained by ICG fluorescence lymphography was published in Radiology.

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2017-12-25
• Study Completion: 2021-03-31
• Last Update Posted: 17 October 2023

Recruitment & Eligibility

• Status: Complete: follow-up complete
• Sex: All
• Target Recruitment: 71

Inclusion Criteria

Not provided

Exclusion Criteria

1. Pregnancy or possible pregnancy 2. The status of immunodeficiency due to neutropenia and so on. 3. Complications that make imaging difficult (e.g. inability to maintain the posture). 4. In cases where it is judged by the research director or the attending physician that it is inappropriate for carrying out this research (e.g. having trouble with the subject's physical condition by keeping the posture during the imaging).

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
The capability of the photoacoustic imaging system for visualizing the lymph-vessel lesion of the patients

Secondary Outcome Measures

Name	Time	Method
1. The relationship between the photoacoustic images and the images by other modalities 2. The relationship between the characteristics of the examinees and the photoacoustic images.