Comparison of the effect of Ketamine and Dexamethasone in combination with Lidocaine on the onset and duration of Axillary block in soft tissue surgery of forearm and hand

Not Applicable

Conditions: Soft tissue injury of forearm and hand.
Superficial injury of forearm, Open wound of forearm, Injury of nerves at forearm level,Injury of blood vessels at forearm level, Injury of muscle and tendon at forearm level, Superficial injury of wrist and hand, Open wound of wrist and hand, Injury of
S50, S51,

Registration Number: IRCT2017030132837N1

Lead Sponsor: Vice chanceler for research, Iran university of medical sciences

Brief Summary: Not available

Detailed Description: Not available

Recruitment & Eligibility

Status: Complete

Sex: All

Target Recruitment: 78

Inclusion Criteria

Consent to participate in research project and cooperation for axillary block; No addiction to opium, Benzodiazepine, Clonidine; Absence of liver and kidney failure, diabetes, cardiovascular and lung diseases, coagulopathy; Lack of any allergic history to local anesthetics; No use of opium in the past 48 hours; Absence of anatomical deformity or burning or infection in block region; No pregnancy in female patients.
Exclusion criteria: The unwillingness or lack of cooperation from the patient during surgery.

Exclusion Criteria

Not provided

Study & Design

Study Type: interventional

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Onset of sensory block. Timepoint: every 3 minutes. Method of measurement: Measuring the length of time between the last injection until complete disappearance of any sense of touch with the stopwatch.;Onset of motor block. Timepoint: every 3 minutes. Method of measurement: Measuring the length of time between the last injection to complete motor paralysis with Stopwatch.;Duration of sensory block. Timepoint: every 3 minutes. Method of measurement: Measuring the time between onset of complete sensory block until the complete return again sense organs with Stopwatch.;Duration of motor block. Timepoint: every 3 minutes. Method of measurement: Measuring the time between onset of complete paralysis to return of complete movement power with stopwtch.

Secondary Outcome Measures

Name	Time	Method
Diastolic blood pressure. Timepoint: 0, 5, 10, 15, 20, 25 minutes after Axillary block. Method of measurement: Non-invasive automatic sphygmomanometer.;Systolic blood pressure. Timepoint: 0, 5, 10, 15, 20, 25 minutes after Axillary block. Method of measurement: Non-invasive automatic sphygmomanometer.;Pulse rate. Timepoint: 0, 5, 10, 15, 20, 25 minutes after Axillary block. Method of measurement: ECG monitoring.;Nystagmus. Timepoint: 0, 5, 10, 15, 20, 25 minutes after Axillary block. Method of measurement: Find the rapid movements of the eyes of horizontal reciprocating.