A clinical trial to compare the effects of low-dose Ketamine and Dexmedetomidine on the need for intraoperative opioids in patients undergoing laparoscopic surgeries
Phase 3
- Conditions
- Health Condition 1: O- Medical and Surgical
- Registration Number
- CTRI/2023/09/057337
- Lead Sponsor
- Sabari Sundaresan
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
Age: 18 - 60 years, ASA 1 and 2 patients, Patients who are undergoing laparoscopic surgeries, Patients without local anaesthetic allergy
Exclusion Criteria
Patients with allergy to any of the study agents, ASA 3 and above patients, BMI >45, History of epilepsy, Patients with cardiac/renal/liver disease.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To compare between Low dose Ketamine and Dexmedetomidine in terms of effective intraoperative opioid requirement (by measuring intraoperative haemodynamics including heart rate, systolic blood pressure, diastolic blood pressure and mean arterial blood pressure)Timepoint: Baseline (0 minute), 5 minutes, 10 minutes, 20 minutes, and every 30 minutes until the end of the surgery.
- Secondary Outcome Measures
Name Time Method To compare post operative pain and post operative nausea & vomiting in the groupsTimepoint: At PACU (0 minute, 1 hour, 2 hours, 3 hours). <br/ ><br>After shifting to ward (6 hours, 12 hours)