The Effect of Anaesthetic Drugs on Recovery in Patients Undergoing Cancer surgery
Not Applicable
Completed
- Conditions
- Health Condition 1: null- GASTRO INTESTINAL MALIGNANCY SURGERIES
- Registration Number
- CTRI/2018/02/011880
- Lead Sponsor
- All India Institute of Medical Sciences Bhubaneswar
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 84
Inclusion Criteria
All adults patients between 18 to 70 years undergoing open GI malignancy surgeries of American Society of Anesthesiologists I & II
Surgeries that are expected to last less than 6 hrs
Exclusion Criteria
Refusal for the consent
Emergency surgeries and re-do surgeries
Patients having any coagulopathies
Diabetic patients
Contraindications to dexmedetomidine and ketamine
Contraindications to epidural
Patients who has received these drugs previously within one month
Known allergic to ketamine and dexmedetomidine.
Patients not extubated for >6 hrs after reversal
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method 1.To assess the effect of infusion of a low dose of ketamine and dexmedetomidine infusions vs placebo on the time to passage of first flatus and/or stools in patients undergoing GI malignancy surgeries.Timepoint: Post - Operatively 24 hrs to 72 hrs
- Secondary Outcome Measures
Name Time Method 1.Total intra-operative & post-operative analgesic used (fentanyl & epidural) <br/ ><br>2.Post op pain & PONV <br/ ><br>3.Duration of ICU stay & time to hospital discharge <br/ ><br>4.Time to extubation after reversal <br/ ><br>5.Any other adverse eventsTimepoint: post-operatively upto 48 hrs