ongitudinal characterization of the sensory phenotype of lipohyperplasia dolorosa (LiDo) patients during weight loss and subsequent liposuction.

niversität zu Köln0 个研究点目标入组 150 人开始时间: 2023年3月6日最近更新: 2024年8月19日

适应症

试验速览

暂无简介。

•Generally: female, age between 18-40 years, present signed and irrevoked informed consent.
•For LiDo patients for weight reduction: medical diagnosis Lipohyperplasia dolorosa (LiDo), coincident obesity BMI > 40,
•For the weight loss group: study-independent planned weight loss to achieve BMI <40 required for lymphatic liposculpture.
•For LiDo patients for lymphologic liposculpture: physician diagnosis of lipohyperplasia dolorosa (LiDo),
•For the surgery group: lymphological liposculpture planned for study-independent reasons, no coincident obesity; BMI <40.
•For obese patients: No medical diagnosis of lipohyperplasia dolorosa (LiDo), obesity BMI > 40.

•Limitation of the ability to communicate (language barrier, cognitive barriers, ...).
•Diseases affecting the sensory nervous system (e.g. Parkinson's disease, multiple sclerosis, radiculopathy, injuries of nerves innervating the sensory area of different genesis, diabetic polyneuropathy, peripheral polyneuropathies of different genesis, etc.).
•skin stresses on the areas of measurement
•topical application of analgesics to the areas of measurement (e.g. plasters, creams, ...)
•diagnosed coagulation or wound healing disorder
•other known alteration in pain perception or another diagnosed pain disorder
•Liposuction already performed prior to study inclusion

发起方

niversität zu Köln