ongitudinal characterization of the sensory phenotype of lipohyperplasia dolorosa (LiDo) patients during weight loss and subsequent liposuction.

niversität zu Köln0 sites150 target enrollmentMarch 6, 2023

Overview

No summary available.

Registry

who.int

Start Date

March 6, 2023

End Date

TBD

Last Updated

last year

Study Type

Observational

Sex

Female

Sponsor

niversität zu Köln

•Generally: female, age between 18\-40 years, present signed and irrevoked informed consent.
•For LiDo patients for weight reduction: medical diagnosis Lipohyperplasia dolorosa (LiDo), coincident obesity BMI \> 40,
•For the weight loss group: study\-independent planned weight loss to achieve BMI \<40 required for lymphatic liposculpture.
•For LiDo patients for lymphologic liposculpture: physician diagnosis of lipohyperplasia dolorosa (LiDo),
•For the surgery group: lymphological liposculpture planned for study\-independent reasons, no coincident obesity; BMI \<40\.
•For obese patients: No medical diagnosis of lipohyperplasia dolorosa (LiDo), obesity BMI \> 40\.

•Limitation of the ability to communicate (language barrier, cognitive barriers, ...).
•Diseases affecting the sensory nervous system (e.g. Parkinson's disease, multiple sclerosis, radiculopathy, injuries of nerves innervating the sensory area of different genesis, diabetic polyneuropathy, peripheral polyneuropathies of different genesis, etc.).
•skin stresses on the areas of measurement
•topical application of analgesics to the areas of measurement (e.g. plasters, creams, ...)
•diagnosed coagulation or wound healing disorder
•other known alteration in pain perception or another diagnosed pain disorder
•Liposuction already performed prior to study inclusion