Clinical Study on Tiaoying Zengye Decoction in Treating Constipation Caused by Clozapine
- Conditions
- Clozapine
- Registration Number
- ITMCTR2200006823
- Lead Sponsor
- Shanghai jing'an mental health center
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- All
- Target Recruitment
- Not specified
?. According to the Diagnostic and Statistical Manual of Mental Diseases (the fifth edition), the patient is diagnosed as a mental disease;
?. Stable treatment of mental illness;
?. Meet the Rome IV diagnostic criteria for functional constipation;
?. Dialectics is yin deficiency;
(5) Aged between 18 and 65;
(6) Take clozapine treatment, and use it steadily for = 1 month
(7) Be able to read and understand the informed consent form, voluntarily participate in the test and sign the informed consent form;
(8) There are no serious diseases of the center of gravity, liver, kidney, hematopoietic system and other influences;
(9) No use of prokinetic drugs, microecological agents and other drugs that significantly affect defecation
?. Those who do not meet the inclusion criteria;
?. Unstable period of chronic somatic diseases;
(3) Pregnant or lactating women;
?. Allergic system or allergy to multiple drugs;
?. Those who cannot use drugs as required, cannot judge the efficacy, or have incomplete data that affect the efficacy or safety judgment
Study & Design
- Study Type
- Interventional study
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Defecation situation;Patient Assessment of Constipation symptom (PAC-SYM);
- Secondary Outcome Measures
Name Time Method Positive and Negative Symptom Scale (PANSS);Treatment Emergent Symptom Scale (TESS);