A study investigating the possible relation between inter-subject variation in parameters of whole saliva, pellicle and differences in susceptibility to erosio
- Conditions
- tandweefseldental erosionwear
- Registration Number
- NL-OMON32183
- Lead Sponsor
- niversitair Medisch Centrum Groningen
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- Not specified
- Target Recruitment
- 50
Inclusion Criteria
Adults with an ASA score of 1 with a rehabilited dentition
Exclusion Criteria
An ASA score of 2 or higher, severe periodontal disease (Dutch periodontal screening index, DPSI > 2) and an unrehabilitated dentition
Study & Design
- Study Type
- Observational non invasive
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method <p>From all participants the saliva total protein concentration will be<br /><br>determined. Also the loss of hydroxyapatite after an erosive challenge will be<br /><br>measured.<br /><br>The correlation between the total protein concentration of saliva and the<br /><br>susceptibility to erosive wear will be calculated. </p><br>
- Secondary Outcome Measures
Name Time Method <p>From all participants the saliva composition (proteins and minerals), saliva<br /><br>characteristics (pH, buffer capacity, viscosity) and pellicle composition<br /><br>(proteins) will be determined. The correlation between different saliva<br /><br>parameters and the susceptibility to erosive wear will be calculated.</p><br>