A pilot study investigating the possible relation between inter-subject variation in parameters of whole saliva and differences in susceptibility to erosio
Recruiting
- Conditions
- tandweefseldental erosionwear
- Registration Number
- NL-OMON31241
- Lead Sponsor
- niversitair Medisch Centrum Groningen
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- Not specified
- Target Recruitment
- 12
Inclusion Criteria
Adults with an ASA score of 1 with a rehabilitated dentition
Exclusion Criteria
An ASA score of 2 or higher, severe periodontal disease (Dutch periodontal screening index, DPSI > 2) and an unrehabilitated dentition
Study & Design
- Study Type
- Observational non invasive
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method <p>From all participants the saliva composition (proteins and minerals) and saliva<br /><br>characteristics (pH, buffer capacity, viscosity) will be determined. Also the<br /><br>loss of hydroxyapatite after an erosive challenge will be measured.<br /><br>The correlation between different saliva parameters and the susceptibility to<br /><br>erosive wear will be calculated. Depending on this correlation and the spread<br /><br>of the data a power analysis will be performed and the sample size will be<br /><br>determined. </p><br>
- Secondary Outcome Measures
Name Time Method <p>nvt</p><br>