Influence of stay in high altitudes on the expression and function of FGF-23 in healthy subjects

• Conditions: Healthy volunteers; E83.3; W94; Disorders of phosphorus metabolism and phosphatases; Exposure to high and low air pressure and changes in air pressure

• Registration Number: DRKS00012771
• Lead Sponsor: niversität des Saarlandes

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2017-08-14
• Study Completion: 2017-08-26
• Results First Posted: 2019-09-09
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Complete
• Sex: All
• Target Recruitment: 8

Inclusion Criteria

• normal kidney function (eGFR > 60 ml/min/1,73 m²),
• women of childbearing potential must agree effective measures of birth control in the 8 weeks before participating in this study

Exclusion Criteria

• malignancy,
• acute or chronic inflammatory diseases,
• congestive heart failure,
• chronic obstructive pulmonary disease,
• coronary heart disease (previous history of myocardial infarction, coronary intervention or coronary artery bypass graft surgery),
• cerebrovascular disorders (history of stroke, surgery of A. carotis or intervention on A. carotis),
• peripheral artery occlusive disease,
• presence or risk factors for a high altitude disease.

Study & Design

• Study Type: observational
• Study Design: Not specified