Effects of acute altitude exposure on non-invasively measured pulmonary shunt volume in healthy individuals compared with patients with chronic obstructive pulmonary disease (COPD)
Not Applicable
Suspended
- Conditions
- J44.9Chronic obstructive pulmonary disease, unspecified
- Registration Number
- DRKS00033737
- Lead Sponsor
- MU-Klinikum, Medizinische Klinik und Poliklinik V
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Suspended
- Sex
- All
- Target Recruitment
- 40
Inclusion Criteria
Healthy subjects: minor illnesses not relevant to the study (e.g. stable hypothyroidism, orthopaedic complaints), near-normal lung function
Subjects with COPD: diseases not relevant to the study (e.g. stable hypothyroidism, orthopaedic complaints)
Exclusion Criteria
Healthy subjects: Fear of travelling on cable cars, clinically manifest heart disease (e.g. coronary heart disease) or other serious illnesses with the risk of acute deterioration
Subjects with COPD: Fear of travelling on cable cars, FEV1 <50 %,
Need for or already established long-term oxygen therapy, multiple exacerbations within a year, clinically manifest heart disease (e.g. coronary heart disease)
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method The aim of the study is to use the ALPE and capnovolumetry measurement methods for the first time to asess pulmonary shunt volume in a comparison of lowland and altitude conditions
- Secondary Outcome Measures
Name Time Method Validity of the results in comparison of the measurement methods