Comparing of Valproate with Placebo in Reducing Methamphetamine Craving
Not Applicable
- Conditions
- Methamphetamine Dependency.Mental and behavioural disorders due to use of other stimulants, including caffeine.Dependence syndrome
- Registration Number
- IRCT201406027841N7
- Lead Sponsor
- Isfahan University of Medical Sciences, Behavioral Sciences Research Center
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 40
Inclusion Criteria
men and women age 18–40 years old; diagnosed with methamphetamin dependency according to DSM-IV criteria; informed acceptance to comply with study procedures. Exclusion criteria: sever medical illness that would impair the ability to participate safely in the study; a current neurological or axis I psychiatric disorders not due to substance abuse (e.g., schizophrenia, dementia) that would impair ability to participate safely in the study; current pregnancy or nursing in women; current serious suicidal intention or plan; more than 3 times elevation of AST and ALT at screening; subjects who met DSM-IV criteria for opiates dependence.
Exclusion Criteria
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Methamphetamine Craving. Timepoint: At screening and every 2 weeks up to 4 months. Method of measurement: Cocaine Craving Questionnaire-Brief (CCQ-Brief).
- Secondary Outcome Measures
Name Time Method Drowsiness. Timepoint: At screening and every 2 weeks up to 4 months. Method of measurement: History and Physical examination.;Dyspepsia. Timepoint: At screening and every 2 weeks up to 4 months. Method of measurement: History and Physical examination.;Weight gain. Timepoint: At screening and every 2 weeks up to 4 months. Method of measurement: History and Physical examination.;Tremor. Timepoint: At screening and every 2 weeks up to 4 months. Method of measurement: History and Physical examination.