The Evaluation of Effect of Addition of Different Doses of Verapamil to 1.5% Lidocaine on Sensory and Motor Axillary Block
Phase 2
- Conditions
- regional anesthesia.
- Registration Number
- IRCT138903094050N1
- Lead Sponsor
- Iran University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 92
Inclusion Criteria
INCLUSION CRITERIA: 1) Upper extrimities surgery including: Hand, Wrist & Forearm 2) Age upper than 18 & lower than 45 3) ASA I & II (American Society of Anesthesia 1 & 2 ) 4) Patient's consent to enter the studyEXCLUSION CRITERIA: 1) Underlying diseases (Hypertension, Diabetes mellitus, Liver diseases, Renal diseases, Coagulopathy) 2) Addiction (opioids & Alcohol) 3)Not consent to enter the study 4) Morbid obesity (weight more than 115 kg) 5)Allergy to local anesthetic drugs 6) Peripheral neuropathy 7) Local infection at injection site 8) Pregnancy
Exclusion Criteria
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Evaluation the time of onset & duration of sympathetic block. Timepoint: Interval time: 0,5,10,15,20,30,45,60,75 minutes & every 15 minutes thereafter after blocking. Method of measurement: Sympathetic block: Alcohol test.;Evaluation the time of onset & duration of sensory & motor block. Timepoint: Interval time: 0,5,10,15,20,30,45,60,75 minutes & every 15 minutes thereafterafter blocking. Method of measurement: Sensory block: Pin prick test/ Motor block: Fingers movement.;Evaluation the duration & quality of analgesia. Timepoint: Interval time: 0,5,10,15,20,30,45,60,75 minutes & every 15 minutes thereafter after blocking and for analgesia 2,4,6,12 ,24 houres in recovery and thereafter. Method of measurement: Analgesia: VAS score.
- Secondary Outcome Measures
Name Time Method Blood pressure (systolic, disatolic). Timepoint: Just before & after & 15, 30, 45, 60 minutes after axillary block & at the end of surgery and in recovery. Method of measurement: Non invasive blood pressuer automatic monitoring.;Mean arterial pressure. Timepoint: Just before & after & 15, 30, 45, 60 minutes after axillary block & at the end of surgery and in recovery. Method of measurement: Non invasive blood pressuer automatic monitoring.;Heart Rate. Timepoint: Just before & after & 15, 30, 45, 60 minutes after axillary block & at the end of surgery and in recovery. Method of measurement: Non invasive blood pressuer & Heart rate automatic monitoring.