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Comparison Of Two Different Drugs For Hormone Replacement In Women With Premature Ovarian Insufficiency

Not Applicable
Conditions
Health Condition 1: N912- Amenorrhea, unspecified
Registration Number
CTRI/2020/07/026376
Lead Sponsor
Maulana Azad Medical College
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
ot Yet Recruiting
Sex
Not specified
Target Recruitment
0
Inclusion Criteria

Women with premature ovarian insufficiency attending Gynaecology and Gynae- Endocrinology OPD in Lok Nayak Hospital.

Exclusion Criteria

1. Known allergies to the two progesterone preparations being studied.

2. Contraindicatin to use of hormone preparation- breast cancer, liver disease, thrombophilia.

3. patients with untreated hypothyroidism.

Study & Design

Study Type
Observational
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Effect of two progesterone preparations on: <br/ ><br>1. Quality and duration of menstrual bleeding. <br/ ><br>2. Endometrial thickness on day 21(+/- 1 day) on USG.Timepoint: 1st, 2nd and 3rd month of each progesterone preparation.
Secondary Outcome Measures
NameTimeMethod
1. Progesterone related subjective effects during the period of intake of the two progesterone preparations. <br/ ><br>2. Effect on lipid profile with two progesterone preparations. <br/ ><br>3. Patient satisfaction regarding their menstrual flow with the two progesterone preparations.Timepoint: At enrollment, at every month, and end of 3rd month of each progesterone preparation.
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