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Effect of medroxyprogesterone acetate in the prevention of premature LH surge in IVF cycles

Not Applicable
Recruiting
Conditions
infertility.
Female infertility, unspecified
N97.9
Registration Number
IRCT20191205045621N2
Lead Sponsor
Shiraz University of Medical Sciences
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Recruiting
Sex
Female
Target Recruitment
100
Inclusion Criteria

age under 42 years
regular menstrual cycles over the previous 3-month period
antral follicle count (AFC) of 7-24 on menstrual cycle day 2–3
Normal TSH and Prolactin levels

Exclusion Criteria

endometriosis grade 3 or higher
diagnosis of polycystic ovarian syndrome
presence of ovarian cyst
hormone treatment receipt within the previous 3-month period
low ovarian reserve (AMH<1.1 or AFC<7)
any contraindication to ovarian stimulation treatment
basal serum FSH concentration of more than 10 IU/L

Study & Design

Study Type
interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
umber of oocytes retrieved. Timepoint: on day of oocyte retrieval. Method of measurement: count.
Secondary Outcome Measures
NameTimeMethod
umber of mature oocytes. Timepoint: on day of oocyte retrieval. Method of measurement: count.;Clinical pregnancy. Timepoint: 3 weeks after IVF. Method of measurement: Measurement of beta-hCG.;Embryos number. Timepoint: after 24 hours and day 5. Method of measurement: microscopic evaluation.;Fertilization rate. Timepoint: 24 hours after intra-cytoplasmic sperm injection. Method of measurement: microscope.;Implantation rate. Timepoint: 2 weeks after embryo transfer. Method of measurement: Measurement of beta-hCG.
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