Evaluation of Thromboelastometry in Sepsis in Correlation to Bleeding During Invasive Procedures

University Hospital, Motol0 sites76 target enrollmentJanuary 2013

ConditionsThrombelastography Sepsis

Overview

Phase: Not Applicable
Intervention: Not specified
Conditions: Thrombelastography
Sponsor: University Hospital, Motol
Enrollment: 76
Primary Endpoint: incidence of bleeding complications
Status: Completed
Last Updated: 7 years ago

Overview Investigators Eligibility Criteria Outcomes Similar Trials

Overview

Brief Summary

The purpose of this study is to analyze occurence of bleeding complications during invasive procedures in septic patients with normal tromboelastometry results despite prolonged standard coagulation tests results

Registry

clinicaltrials.gov

Start Date

January 2013

End Date

October 2016

Last Updated

7 years ago

Study Type

Observational

Sex

All

Investigators

Sponsor

University Hospital, Motol

Responsible Party

Principal Investigator

Durila Miroslav MUDr. Ph.D.

clinical researcher

University Hospital, Motol

Eligibility Criteria

Inclusion Criteria

•sepsis/septic shock
•prolonged PT-INR (international normalized ratio) ≥ 1.3
•normal ROTEM-EXTEM results.

Exclusion Criteria

•patients on antiplatelet drugs or anticoagulant therapy (heparin, vitamin K antagonists...)
•patients with cirrhosis

Outcomes

Primary Outcomes

incidence of bleeding complications

Time Frame: 2013 - 2016

In our group of 76 septic patients who had normal values of EXTEM despite prolonged INR/PR invasive procedures were performed without severe bleeding.