The Effect of Physical Activity on The Response of Autonomic Nervous System in Individuals With Autism Spectrum Disorders of Different Age Groups
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Neurodevelopmental Disorders
- Sponsor
- University of Jazan
- Enrollment
- 200
- Locations
- 1
- Primary Endpoint
- ECG measurements
- Status
- Completed
- Last Updated
- 2 years ago
Overview
Brief Summary
This study will investigate the effect of physical activity on autism spectrum disorder (ASD) in individuals with ASD of different age groups through measuring the hemodynamic, heart activity and respiratory system parameters.
Detailed Description
One hundred participants will be included in this study. One hundred typically developed children or control group and one hundred children with ASD group. The age range of participants will be 4 - 18 years old. The participants in both control and ASD groups will be randomly divided into 4 subgroups according to their age (4-7 years old, 7-10 years old, 10-13 years old and, 14-18 years old). Also, ASD group will be categorized according to the symptoms severity using the childhood autism rating scale (CARS). Participants will be excluded if they have any intellectual disability (IQ ≤ 70), co-morbid medical or psychiatric disorders, pervasive developmental disorders (PDD) or Attention-deficit hyperactivity disorders (ADHD). They will also be excluded if they are taking any medications which to affect cardiovascular system, respiratory system, or arousal and balance or any other contraindications to exercises. Wechsler Intelligence Scale for Children-Fourth Edition24 will be used to assess the Intelligence Quotient (IQ).
Investigators
Mohammed Moustafa
Assistant Professor
University of Jazan
Eligibility Criteria
Inclusion Criteria
- •Children with ASD group with the age range of participants will be 4 - 18 years old
- •Typically developed children with the age range of participants will be 4 - 18 years old
Exclusion Criteria
- •Participants will be excluded if they have the following:
- •any intellectual disability (IQ ≤ 70)
- •co-morbid medical or psychiatric disorders.
- •pervasive developmental disorders (PDD) or Attention-deficit hyperactivity disorders (ADHD).
- •They will also be excluded if they are taking any medications which to affect cardiovascular system, respiratory system, or arousal and balance or any other contraindications to exercises.
Outcomes
Primary Outcomes
ECG measurements
Time Frame: One minute
A wearable device will be used to collet cardiac ECG data.
Measurements of respiration
Time Frame: 5 minutes
Portable Respiratory Monitor will be used to measure the respiratory activity.
Blood pressure measurement
Time Frame: 5 minutes
Manual sphygmomanometer will be used to measure the blood pressure.