Effect van broccoli zaailingen op ontsteking en insuline gevoeligheid na een testmaaltijd.
Recruiting
- Conditions
- insulin resistance, inflammation
- Registration Number
- NL-OMON20949
- Lead Sponsor
- niversity Medical Center Groningen
- Brief Summary
/A
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- Not specified
- Target Recruitment
- 12
Inclusion Criteria
1. Healthy male volunteer aged 18 to 30 and BMI 18-25 kg/m2, extremities included;
2. Not involved in intensive sportive activities more than twice a week (e.g. playing football,
tennis, running, race-cycling, swimming);
Exclusion Criteria
1. Not being able to fast overnight (10 hours);
2. Vegetarians;
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method The main outcomes of this study are inflammation and insulin sensitivity. Inflammation will be addressed by PBMC activation as measured by nuclear translocation of NF-kappaB, plasma cytokine levels and insulin sensitivity as determined by plasma concentrations of glucose and insulin as well as the uptake of glucose in tissues.
- Secondary Outcome Measures
Name Time Method Sulforaphane kinetics, measured in plasma and urine.