Collection of Cerebrospinal Fluid in Healthy Children
Overview
- Phase
- N/A
- Intervention
- Not specified
- Conditions
- Late Infantile Neuronal Ceroid Lipofuscinosis
- Sponsor
- Weill Medical College of Cornell University
- Enrollment
- 32
- Locations
- 1
- Primary Endpoint
- Cerebrospinal fluid (CSF)
- Status
- Terminated
- Last Updated
- 10 years ago
Overview
Brief Summary
The purpose of this study is to obtain cerebrospinal fluid from healthy children already undergoing a lumbar puncture procedure at New York Presbyterian Hospital, to act as healthy controls when compared to children with late infantile neuronal ceroid lipofuscinosis (LINCL), a fatal neurodegenerative disease.
Detailed Description
obtain cerebrospinal fluid from healthy children already undergoing a lumbar puncture procedure at New York Presbyterian Hospital, to act as healthy controls when compared to children with late infantile neuronal ceroid lipofuscinosis (LINCL), a fatal neurodegenerative disease.
Investigators
Eligibility Criteria
Inclusion Criteria
- •Males and females, ages 2 yrs to 8 yrs
- •Children already undergoing a lumbar puncture procedure for clinical or diagnostic purposes
Exclusion Criteria
- •Presence of any significant neurological diseases, as judged by the co-investigators
- •Presence of any significant medical conditions including cancer
Outcomes
Primary Outcomes
Cerebrospinal fluid (CSF)
Time Frame: 1 time point (once)
The primary study endpoint is the metabolic profiling of 32 samples of cerebrospinal fluid from healthy subjects, in comparison to 32 samples of CSF from children with LINCL, to determine whether there are biomarkers found in the cerebrospinal fluid that are associated with LINCL.