A Children's Oncology Group Protocol for Collecting and Banking Pediatric Brain Tumor Research Specimens
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Childhood Atypical Teratoid/Rhabdoid Tumor
- Sponsor
- Children's Oncology Group
- Enrollment
- 1258
- Locations
- 187
- Primary Endpoint
- Collection of brain tumor tissue and an accompanying blood sample from pediatric patients with brain tumors treated at Children?s Oncology Group institutions
- Status
- Completed
- Last Updated
- 7 years ago
Overview
Brief Summary
The purpose of this study is to collect and store brain tissue samples and blood from children with brain cancer that will be tested in the laboratory. Collecting and storing samples of tumor tissue and blood from patients to test in the laboratory may help the study of cancer in the future.
Detailed Description
OBJECTIVES: I. Collect brain tumor tissue and an accompanying blood sample from pediatric patients with brain tumors treated at Children?s Oncology Group institutions. II. Provide a repository for long-term storage of specimens from these patients. III. Make these specimens available to qualified researchers to understand the biology of pediatric brain tumors. OUTLINE: This is a multicenter study. Brain tumor tissue and blood specimens are collected from patients and banked for future study.
Investigators
Eligibility Criteria
Inclusion Criteria
- •Diagnosis of brain tumor
- •Previously treated at a Children?s Oncology Group (COG) institution
- •Patients are eligible at time of diagnosis, second-look surgery, recurrence, or development of a second malignant neoplasm
- •Must have brain tumor biological specimens derived from primary tumors of the CNS available for submission
Exclusion Criteria
- Not provided
Outcomes
Primary Outcomes
Collection of brain tumor tissue and an accompanying blood sample from pediatric patients with brain tumors treated at Children?s Oncology Group institutions
Time Frame: Up to 16 years
Creation of a repository for long-term storage of these specimens
Time Frame: Up to 16 years
Making these specimens available to qualified researchers to understand the biology of pediatric brain tumors
Time Frame: Up to 16 years