Effects of Aerobic Versus Resistance Training in Post Percutaneous Coronary Intervention Obese Patients

Not Applicable

Completed

• Conditions: Cardiovascular Diseases
• Interventions: Other: Resistance Training; Other: Aerobic Training

• Registration Number: NCT06308276
• Lead Sponsor: Riphah International University

Brief Summary

The randomized clinical trial (RCT) endeavors to enroll 50 participants, divided equally into aerobic exercise and resistance exercise groups. The study employs rigorous tools such as blood pressure measurement, SF-36 questionnaire, and the Six-Minute Walk Test (6MWT) to assess VO2max.

Detailed Description

The randomized clinical trial (RCT) endeavors to enroll 50 participants, divided equally into aerobic exercise and resistance exercise groups. The non-probability convenient sampling technique, followed by random allocation using a lottery method, ensures a diverse yet unbiased sample. Will be conducted at the Sialkot Medical and Physiotherapy Centre, the inclusion criteria will focus on post-PCI patients aged 40-60, presenting with a BMI of 30 or higher. The study employs rigorous tools such as blood pressure measurement, SF-36 questionnaire, and the Six-Minute Walk Test (6MWT) to assess VO2max. The aerobic exercise group undergoes sessions three times a week, progressively increasing in duration and intensity, emphasizing activities like brisk walking and cycling. The resistance exercise group follows a similar schedule, engaging in full-body resistance exercises targeting major muscle groups. Both groups undergo assessments using cardiopulmonary exercise testing (CPET) to determine exercise tolerance accurately.

Study Timeline

• Study Start: 2024-03-01
• Study First Submitted: 2024-03-04
• Study First Submitted QC: 2024-03-12
• Study First Posted: 2024-03-13
• Primary Completion: 2024-06-05
• Study Completion: 2024-06-15
• Status Verified: 2024-07
• Last Update Submitted: 2024-07-22
• Last Update Posted: 2024-07-23

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 50

Inclusion Criteria

• Age: Participants must be between 40 and 60 years old.
• Gender: Male and female both.
• Cardiovascular Status: Post Percutaneous Coronary Intervention (PCI) patients with a documented history of coronary artery disease
• Participants who are at least three months post PCI to ensure stabilization of their cardiovascular condition.
• Obesity: Participants must have a Body Mass Index (BMI) equal to or greater than 30 kg/m², indicating obesity.
• Health Status: Participants should be in stable health condition to participate in moderate physical activities.
• Willingness to Participate: Participants must provide informed consent and be willing to comply with the study protocol, including attending scheduled exercise sessions and follow-up assessments.
• Participants capable of engaging in either aerobic or resistance training, were assessed by a physical activity readiness questionnaire (PAR-Q).

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Exclusion Criteria

• Participants with severe physical limitations, disabilities, or musculoskeletal disorders that would prevent them from engaging in aerobic and resistance exercises.
• Individuals with a history of substance abuse or current substance abuse issues that might interfere with their ability to participate or adhere to the study protocol.
• Patients with Neurological diseases
• Patients with severe or unstable heart conditions, recent heart attack, or heart failure

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Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Group B	Resistance Training	Full body resistance exercise targeting major muscle groups, including squats, lunges, chest presses, rows, and core exercises
Group A	Aerobic Training	Brisk walking, jogging, cycling, or low-impact aerobics

Primary Outcome Measures

Name	Time	Method
Blood Pressure	4 Weeks	Blood pressure is a crucial physiological parameter often employed as a data collection tool in research, particularly in studies focused on cardiovascular health and related interventions.
Six Minute Walk Test	4 Weeks	The 6-minute walk test (6MWT) serves as a valuable and widely used data collection tool in research, particularly in studies assessing functional capacity, exercise tolerance, and overall physical performance.
SF 36 Questionnaire	4 Weeks	The Short Form 36 (SF-36) is a widely used health-related quality of life (HRQoL) questionnaire that serves as a comprehensive data collection tool in research studies across various disciplines.

Trial Locations

Locations (1)

Sialkot Medical and Physiotherapy Center; 🇵🇰 Sialkot, Punjab, Pakistan