Treating cocaine dependence by targeting underlying cognitive processes

Completed

• Conditions: cocaïnemisbruik en cocaïneafhankelijkheid; addiction; cocaine dependence

• Registration Number: NL-OMON41639
• Lead Sponsor: Academisch Medisch Centrum

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 23 April 2024

Recruitment & Eligibility

• Status: Completed
• Sex: Not specified
• Target Recruitment: 50

Inclusion Criteria

male, 18-60 years old, using cocaine at least 4 times per maand

Exclusion Criteria

Suffering from a neurological or medical illness; lifetime history of head injury with loss of consciousness for more than 5 minutes; unstable medical illness (e.g., hypertension, diabetes, myocardial infarction); severe stomach problems or ulcers; exclusion criteria for MR imaging such as the presence of non-removable metal objects (e.g. arteriovenous clips, pacemakers) and claustrophobia interfering with MR investigation.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>- cocaine use<br /><br>- craving<br /><br>- working memory<br /><br>- glutamate concentrations in dACC and striatum</p><br>

Secondary Outcome Measures

Name	Time	Method
<p>none</p><br>