Preoperative biliary drainage for pancreato-biliary tumors causing obstructive jaundice; DRainage vs Operation.
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 210
研究概览
简要总结
Incidence and management of pancreatic leakage after pancreatoduodenectomy. de Castro SM, Busch OR, van Gulik TM, Obertop H, Gouma DJ. Br J Surg. 2005 Sep;92(9):1117-23.
Delayed massive hemorrhage after pancreatic and biliary surgery: embolization or surgery? de Castro SM, Kuhlmann KF, Busch OR, van Delden OM, Lameris JS, van Gulik TM, Obertop H, Gouma DJ. Ann Surg. 2005 Jan;241(1):85-91.
Recurrent disease after microscopically radical (R0) resection of periampullary adenocarcinoma in patients without adjuvant therapy. de Castro SM, Kuhlmann KF, van Heek NT, Busch OR, Offerhaus GJ, van Gulik TM, Obertop H, Gouma DJ. J Gastrointest Surg. 2004 Nov;8(7):775-84; discussion 784.
Surgical management of neoplasms of the ampulla of Vater: local resection or pancreatoduodenectomy and prognostic factors for survival. de Castro SM, van Heek NT, Kuhlmann KF, Busch OR, Offerhaus GJ, van Gulik TM, Obertop H, Gouma DJ. Surgery. 2004 Nov;136(5):994-1002
Management of bleeding and leakage after pancreatic surgery. de Castro SM, Busch OR, Gouma DJ. Best Pract Res Clin Gastroenterol. 2004 Oct;18(5):847-64.
研究设计
- 研究类型
- Interventional
入排标准
入选标准
- •1. Clinical diagnosis of obstructive jaundice due to a pancreatic head or periampullary tumor;
- •2. A serum bilirubin level of > 40 µmol/l and < 250 µmol/l at randomization;
排除标准
- •1. Age > 85 years or severe co-morbidity (Karnofsky <50%) and other contra indications for major surgery;
- •2. Cholangitis/infection;