TO Evaluate the clinical efficacy of ghrita bhrista Jyothishmathi patra with durva swarasa in Artava kshaya in poly cystic ovarian syndrome-A Pilot study

Artava Kshaya is described as a condition where there is diminution or reduction in menstrual flow,irregularity or cessation of menstruation and disruption in the normal menstrual cycle1.PCOS(polycystic ovarian syndrome) is the most common endocrine disorder in a women of reproductive age.Diagnosis is based upon the presence of any two of the following criteria 1)Oligoand/anovulation  2)Hyperandrogenism (clinical and/or biochemical). 3)polycystic ovaries.Ovarian volume increased≥10cm3. Presence of multiple(≥12)follicles cysts measuring about 2-9mm in diameter around the cortex2. Incidence of PCOS is estimated to be around 5-10% among women of reproductive age and Prevalence rates for PCOS range from 6%-20% with variations influenced by factors such as ethnicity and regional demographics. specific populations, particularly those with family history of PCOS or associated metabolic conditions may exhibit higher Prevalence rates3. Artava Kshaya can be understood as a vata-kaphaja vikara,where vata governs physiological functions with apana vata ensuring the proper flow of artava. Kapha with its Avrodhaka guna can block the Artava vaha srotas, contributing the pathogenesis of Artava Kshaya along with Vata.In Bhaisajya Ratnavali acharya has mentioned that Jyothishmati patra (Celastrus paniculatus) roasted with Goghrita ground with durva swarasa (Cynodon dactylon) act as artavapravartaka4. Jyotishmati ( Celastrus paniculatus) with its katu-tiktarasa, teekshnaguna, ushnaveerya and katuvipaka helps in vilayana of kapha and alleviating vata dosha there by clearing obstructions, it also promotes agnivardhana, amapachana, leading to proper formation of rasadidhatu. since Artava is the upadhatu of rasadhatu, this process supports proper artava formation5.