Effect of cream with tranexamic acid on post-inflammatory pigmentation after Q-switch ruby laser treatment
- Conditions
- Senile lentigineSenile lentigine, solar lentigines
- Registration Number
- JPRN-jRCT1030200265
- Lead Sponsor
- Bunsho Kao
- Brief Summary
Regarding the incidence of PIH after Q-switched ruby laser treatment for senile pigmentation, the incidence of PIH was significantly reduced by using a cream containing tranexamic acid from before the laser treatment.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 42
1) Japanese and over 20
2) Senile pigmented spots on the face
3) According to the doctor's instructions, you can continue to use the research item twice daily.
4) Agree with regular visits
1) Received beauty (whitening) treatment within the last 3 months
2) Used whitening cosmetics within the last 3 months
3) In the past, external use of tranexamic acid caused dermatitis
4) Experienced dermatitis due to hair dye
5) Vitiligo
6) History of Vitiligo
7) Precancerous lesion, malignant tumor, or suspected
8) Hemorrhagic disease
9) Melasma
10) Taking a drug that has high photosensitivity or enhances photosensitivity.
11) History of rheumatism and history of oral administration of gold preparation
12) There is a gold thread in the laser irradiation area
13) There is a skin-colored/white tattoo on the laser-irradiated area.
14) Pregnant and possibly pregnant
15) Lactating
16) In addition the doctor determined that it was inappropriate
Study & Design
- Study Type
- Other
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Rate of incidence of post-inflammatory pigmentation one month after laser treatment
- Secondary Outcome Measures
Name Time Method Rate of incidence of post-inflammatory pigmentation pre and post-laser treatment