Micro-RNA 15a-5p dysregulation and its Target Gene in Oral cancer and normal tissue
Not Applicable
Completed
- Conditions
- Health Condition 1: C068- Malignant neoplasm of overlappingsites of other and unspecified parts of mouth
- Registration Number
- CTRI/2022/03/040790
- Lead Sponsor
- DR S PADMAVATHI
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 44
Inclusion Criteria
GROUP A:
INCLUSION:
â?¦Clinically and histologically diagnosed oral carcinoma patients.
GROUP B:
INCLUSION:
Healthy individuals who undergo extraction prior to the commencement of orthodontic procedure without any periodontal diseases.
Exclusion Criteria
GROUP A:
EXCLUSION:
â?¦Patients diagnosed with epithelial tissue disorders and any other oral lesions.
â?¦Patients with no history of treated or untreated malignancies of any other system.
â?¦The patient is not willing to participate.
â?¦Patients diagnosed with any pre-malignant lesions.
GROUP B:
EXCLUSION:
â?¦Patients are not willing to participate.
â?¦Patients diagnosed with other pre-malignant lesions.
â?¦Clinically diagnosed carcinoma patients.
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Dysregulation of miRNA-15a-5p in OSCC compared to normal tissues and the relation with YAP1 gene. <br/ ><br>Timepoint: MONTHS0-67-1213-16 <br/ ><br>NO.OF <br/ ><br>CASES 10 20 14 <br/ ><br>
- Secondary Outcome Measures
Name Time Method Dysregulation of miRNA-15a-5p in OSCC compared to normal tissues and the relation with YAP1 gene. <br/ ><br>Timepoint: MONTHS0-67-1213-16 <br/ ><br>NO.OF <br/ ><br>CASES 10 20 14