MicroRNAs expression analysis in patients undergoing cardiac surgery treated with halogenated anesthetics. Identification of microRNAs related to the cardioprotective effect

FIMABIS0 个研究点开始时间: 2016年9月9日最近更新: 2017年1月31日

适应症

试验速览

暂无简介。

•1. Age = 18 year old.
•2. Elective off-pump coronary artery bypass surgery.
•3. EUROSCORE (European level of risk, useful in the perioperative period of patients undergoing cardiac surgery, validated at medical and scientific level) under 8 (cardiological moderate risk in the perioperative).
•4. Degree of anesthetic risk according to the American Society of Anesthesiologists (ASA) less than 4 (moderate-risk patient high anesthetic).
•Are the trial subjects under 18? no
•Number of subjects for this age range:
•F.1.2 Adults (18-64 years) yes
•F.1.2.1 Number of subjects for this age range 128
•F.1.3 Elderly (>=65 years) no
•F.1.3.1 Number of subjects for this age range

•1. History of adverse reaction to anesthetic drugs.
•2. Severe illness of any organ (lung, liver, kidney), diagnosed preoperatively.
•3. Combined surgery (eg valve repair or carotid surgery).
•4. Patients in situations of hemodynamic instability.
•5. Heart failure or need for use of inotropes or vasoactive pre-intervention.
•6. Treatment with oral antidiabetic drugs at least 48 hours before.
•7. Pre-intervention treatment with eufilina/theophylline.
•8. Inability to grant informed consent.
•9. Pregnancy or breastfeeding.

发起方

FIMABIS