Role of cardiovascular biomarkers in the Periodontal Disease associated to Diabetes

Not Applicable

Recruiting

• Conditions: Periodontal Disease and Diabetes; C07.465.714; C18.452.394.750

• Registration Number: RBR-35szwc
• Lead Sponsor: niversidade Santo Amaro

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2020-02-26
• Last Update Posted: 29 May 2023

Recruitment & Eligibility

• Status: Recruiting
• Sex: Not specified
• Target Recruitment: Not specified

Inclusion Criteria

The study will include patients of both sexes; who follow up at the University of Santo Amaro Dental Clinic - UNISA; aged between 40 and 75 years; with periodontal disease (moderate and advanced); periodontal disease associated or not with diabetes.

Exclusion Criteria

Exclusion criteria include toothlessness; periodontal treatment within the last six months; HIV-positive; positive-hepatitis C virus (HCV) or positive-hepatitis B (HBV); and / or other systemic disease; smoking; gingivitis or mild periodontitis; continued use of anti-inflammatory and / or immunosuppressive medications.

Study & Design

• Study Type: Intervention
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Improvement of inflammatory marker levels after 30 days from the end of periodontal treatment in the periodontal disease group when compared to the periodontal disease + diabetes group, <br>which will be assessed through the levels of inflammatory markers (circulating microparticles and local inflammatory markers in the gingival crevicular fluid).

Secondary Outcome Measures

Name	Time	Method
Secondary outcomes are not expected.