The association between monocyte subsets and coronary plaque characteristics-a retrospective study
Not Applicable
- Conditions
- Angina pectoris with impaired glucose torerance or diabetes mellitus and patients who are suspected that disease
- Registration Number
- JPRN-UMIN000023428
- Lead Sponsor
- Kobe University Hospital department of cardiovascular medicne
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up complete
- Sex
- All
- Target Recruitment
- 65
Inclusion Criteria
Not provided
Exclusion Criteria
1)Patients with renal dysfunction(Creatinin level is more than 2.0mg/ml) or reciving hemodaialysis. 2)the patients who have had heart failure (NYHA >III) 3)patients with any malignant tumor or very ill condition 4)pregnant women or women at risk of becoming pregnant
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method 1.Coronary plaque characteristics using the optical coherence tomography (OCT) and intravascular ultrasound(IVUS) and coronary angiography 2.Association between atherosclerosis assessed by IVUS or OCT and subsets of monocyte. 3.Circadian rhythm in the blood glucose using CGM
- Secondary Outcome Measures
Name Time Method 1.Glucose, IRI, CPR assesed by glucose tolerance test. 2.Intima- media thickness(IMT) assesed by carotid artery ultrasound. 3.Endothelial function assessed by FMD. 4.Inflammatory cell marker associated with arteriosclerosis.