Psycho-biological treatment effects of trauma-focused art therapy in patients with psychological and physical trauma consequences

Not Applicable

Conditions: F43.0
Acute stress reaction

Registration Number: DRKS00022989

Lead Sponsor: Ärztliche Leitung der Klinik fürPsychosomatische Medizin und PsychotherapieKlinikum Nürnberg

Brief Summary: Not available

Detailed Description: Not available

Recruitment & Eligibility

Status: Pending

Sex: Female

Target Recruitment: 128

Inclusion Criteria

Recruitment of patients after potentially traumatizing, critical events that have an increased risk of developing post-traumatic stress disorder Critical events are defined as:
a) miscarriage or stillbirth
b) Incisive cardiac event (e.g. myocardial infarction, resuscitation after cardiac event, aortic dissection)
c) Serious accident (e.g. traffic accident)

Exclusion Criteria

- Male sex
- Acute addiction
- Acute suicidal tendency
- Mental disorders that require permanent medication
- Chronic inflammatory diseases with anti-inflammatory medication
- Dementia
- Insufficient knowledge of the german language
- Non-accessibility of the Klinikum Nürnberg from your place of residence (for outpatient therapy sessions)

Study & Design

Study Type: interventional

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
The primary objective is the severity of posttraumatic stress symptoms after the intervention, measured with the revised version of the Impact of Events Scale (IES-R) (Maercker & Schützwohl, 1998; Weiss & Marmar, 1997) and the German version of the Posttraumatic Diagnostic Survey (PDS)(Ehlers et al., 1996).

Secondary Outcome Measures

Name	Time	Method
Secondary biological targets are neuroendocrine and immunological stress reactivity (measured by cortisol and a-amylase in saliva, and interleukin (IL)-6 and IL-10 in plasma), stress-related DNA damage in single cells in the form of single- and double-strand breaks, and their metabolites (including nitrotyrosine/HO-1/iNOS) by exposure to stress-related radical formation.<br>Secondary psychicological targets are depression and post-traumatic growth.<br><br>Translated with www.DeepL.com/Translator (free version)