Dexamethasone adjuvant therapy and intramuscular ceftriaxone in bacterial meningitis amongst adults in an area of high human immunodeficiency virus (HIV) prevalence in Blantyre, Malawi

Completed

• Conditions: Bacterial Meningitis; Infections and Infestations; Meningitis

• Registration Number: ISRCTN31371499
• Lead Sponsor: College of Medicine Research Committee (Malawi)

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2005-09-07
• Last Update Posted: 13 January 2015

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 420

Inclusion Criteria

All adults admitted to the Queen Elizabeth Central Hospital, Blantyre with a preliminary diagnosis of bacterial meningitis.

Exclusion Criteria

1. Age less than 16 years
2. Steroids received within the 24 hours preceeding admission

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Mortality at 40 days

Secondary Outcome Measures

Name	Time	Method
1. Death or disability at 40 days<br>2. Clinically apparent hearing loss at 40 days<br>3. Death at six months